Journal CME 34.09: The Role of High-Intensity Focused Ultrasound as a Symptomatic Treatment for Parkinson’s Disease

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Journal CME 34.09: The Role of High-Intensity Focused Ultrasound as a Symptomatic Treatment for Parkinson’s Disease

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MR-guided focused ultrasound is a novel, minimally invasive surgical procedure for symptomatic treatment of PD. With this technology, the ventral intermediate nucleus, STN, and internal globus pallidus have been targeted for therapeutic cerebral ablation, while also minimizing the risk of hemorrhage and infection from more invasive neurosurgical procedures. In a double-blinded, prospective, sham-controlled randomized controlled trial of MR-guided focused ultrasound thalamotomy for treatment of tremor-dominant PD, 62% of treated patients demonstrated improvement in tremor scores from baseline to 3 months postoperatively, as compared to 22% in the sham group.

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Faculty: Shayan Moosa, Raul Martínez-Fernández, W. Jeffrey Elias, Marta del Alamo, Howard M. Eisenberg, Paul S. Fishman

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